3:00pm
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4:00pm |
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Neurotransmitter and Ion Channel Asymmetries: Does Experience-Dependent Accrual and Loss Over the Lifespan Predispose Us to Neurodegenerative Disease?
(VTC)
Rosalyn Moran, PhD
Senior Research Associate
Wellcome Trust Centre for Neuroimaging
Institute of Neurology
University College London
Emerging evidence from animal models of neurodegenerative disease points to a spread of pathological markers through synaptic connections in brain networks. In this talk, Dr. Moran will outline an experiential hypothesis of cortical aging and how it predicts that particular cortical pathways are overactive, while other pathways are underactive, with progressing age. Dr. Moran will outline how these pathways are distinct in terms of their neurophysiology and anatomical origin, and how these distinctions may be assayed using a model-based imaging approach in humans, in vivo. Dr. Moran will also present a proposed set of human pharmacological neuroimaging experiments designed to activate networks known to be vulnerable in Parkinson's disease and Alzheimer's disease.
Hosted by: Michael J. Friedlander, PhD, Executive Director, Virginia Tech Carilion Research Institute
More information...
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540-526-2070